Laboratuvar Parametreleri ve Prognostik Skorların Yoğun Bakım Ünitesinde Coronavirüs Hastalığı-19 Hastalarına Yapılan Kardiyopulmoner Resüsitasyonda Etkisi
Amaç: COVID-19 hastalarının yaklaşık üçte biri kritik hastalığa yakalanmaktadır. Modifiye Glasgow prognostik skoru(mGPS) ve modifiye sistemik inflamasyon skoru(mSIS), sistemik inflamasyonu gösterir. Bu çalışmanın amacı, COVID-19 olan ve kardiyopulmoner resüsitasyon(CPR) girişiminde bulunan hastalarda kan değerlerinin karşılaştırılmasıyla mGPS, mSIS ve CPR sonucu(spontan dolaşımın geri dönüşü ya da ölüm) arasındaki ilişkiyi değerlendirmektir.
Gereç ve Yöntem: COVID-19 nedeniyle yoğun bakımda yatışı gereken ve CPR uygulanan 65 hasta geriye dönük olarak tarandı. Hastalar CPR sonrası ölen hastaları kapsayan GroupEX (n=45) ve spontan dolaşımın geri dönüşü sağlanan hastaları kapsayan GroupROSC (ROSC) (n=20) olarak iki gruba ayrıldı. Hastaların mGPS ve mSIS değerleri hesaplandı.
Bulgular: GrupROSC’ da nötrofil yüzdesi, INR ve bilirubin anlamlı düşük; monosit yüzdesi ve albumin anlamlı yüksek olarak saptandı (p< 0.001, p=0.01, p=0.04, p= 0.01, p=0.004 , p<0.001 sırasıyla). Ek olarak, iki grup arasında mGPS' de anlamlı bir fark vardı (p=0,032). ROC analizinde mSIS ve mGPS, GroupEX'te daha yüksek puanlar gösterdi. mSIS duyarlılığı ve özgüllüğü sırasıyla %83,7 ve %68,4 (p=0,34) ve mGPS duyarlılığı ve özgüllüğü sırasıyla %95,3 ve %68,4 (p=0,09) olarak saptandı.
Sonuç: Sonuçlarımıza göre mGPS ve mSIS, CPR sonuç tahminine katkıda bulunabilir.
Atıf yapmak için : Öztürk Sönmez L, Vatansev H, Ayrancı MK, Katipoğlu B, Szarpak L, Evrin T. The Effect of Laboratory Parameters and Prognostic Scores on Cardiopulmonary Resuscitation in Coronavirus Disease-19 Patients in Intensive Care Unit. Mev Med Sci. 2023;3(2):54-60
Mevlana Tıp Bilimleri 2023, Cilt3, Sayı2 E-ISSN: 2757-976X
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